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Advanced filters: Author: Arthur Michaut Clear advanced filters

  • Human presomitic mesoderm cells derived in vitro demonstrate oscillations of the segmentation clock, thus providing a window into an otherwise inaccessible stage of human development.

    • Margarete Diaz-Cuadros
    • Daniel E. Wagner
    • Olivier Pourquié
    Research
    Nature
    Volume: 580, P: 113-118

  • The authors show that metabolic activity leads to an increase in the intracellular pH of neuromesodermal precursors, and that this increase in pH, by allowing post-translational modification of β-catenin, is required for the activation of WNT signalling and mesodermal fate acquisition.

    • Masayuki Oginuma
    • Yukiko Harima
    • Olivier Pourquié
    Research
    Nature
    Volume: 584, P: 98-101