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Showing 1–4 of 4 results
Advanced filters: Author: Arun Durvasula Clear advanced filters

  • Dominance is difficult to measure in natural populations as it is confounded with fitness. Here, Huber et al. developed a new approach to co-estimate dominance and selection coefficients, and found that the observed relationship is best fit by a new model of dominance based on gene expression level.

    • Christian D. Huber
    • Arun Durvasula
    • Kirk E. Lohmueller
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-11

  • A study using population genomic data of domesticated and wild maize shows that purifying selection plays a major role in shaping maize diversity, and the efficacy of purifying selection increased following post-domestication population expansion.

    • Timothy M. Beissinger
    • Li Wang
    • Jeffrey Ross-Ibarra
    Research
    Nature Plants
    Volume: 2, P: 1-7

  • The Impact of Genomic Variation on Function Consortium is combining single-cell mapping, genomic perturbations and predictive modelling to investigate relationships between human genomic variation, genome function and phenotypes and will provide an open resource to the community.

    • Jesse M. Engreitz
    • Heather A. Lawson
    • Ella K. Samer
    Reviews
    Nature
    Volume: 633, P: 47-57