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A spatio-temporal brain miRNA expression atlas identifies sex-independent age-related microglial driven miR-155-5p increase

MicroRNAs regulate brain development and aging. Here, authors show that a spatio-temporal atlas of 15 mouse brain regions reveals sex- and region-specific microRNA patterns, including age-related microglial miR-155-5p increase targeting mTOR.

Annika Engel
Viktoria Wagner
Andreas Keller
ResearchOpen Access17 May 2025
Nature Communications

Volume: 16, P: 1-17

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A spatio-temporal brain miRNA expression atlas identifies sex-independent age-related microglial driven miR-155-5p increase

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