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Showing 1–3 of 3 results
Advanced filters: Author: Ashley M. Rozario Clear advanced filters

  • Viral proteins can achieve high multifunctionality, but mechanisms are poorly understood. This study shows structural flexibility of rabies virus P protein enables RNA binding and phase separation to expand functions by infiltrating host condensates.

    • Stephen M. Rawlinson
    • Shatabdi Chakraborty
    • Gregory W. Moseley
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-23

  • Many RNA viruses that replicate in the cytoplasm express proteins that localize to nucleoli, but the nucleolar functions remain largely unknown. Here, the authors show that the Henipavirus matrix protein mimics an endogenous Treacle partner of the DNA-damage response, resulting in suppression of rRNA biogenesis.

    • Stephen M. Rawlinson
    • Tianyue Zhao
    • Gregory W. Moseley
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • This Perspective highlights the fundamental questions in the regeneration process from start to finish and how they might be addressed to facilitate cross-species studies.

    • Ashley W. Seifert
    • Elizabeth M. Duncan
    • Ricardo M. Zayas
    ReviewsOpen Access
    Communications Biology
    Volume: 6, P: 1-13