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Advanced filters: Author: Athul Sanjeev Clear advanced filters

  • In a cynomolgus macaque model, CRISPR base editors delivered in lipid nanoparticles are shown to efficiently and stably knock down PCSK9 in the liver to reduce levels of PCSK9 and low-density lipoprotein cholesterol in the blood.

    • Kiran Musunuru
    • Alexandra C. Chadwick
    • Sekar Kathiresan
    Research
    Nature
    Volume: 593, P: 429-434