Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: Aurélie Hintermann Clear advanced filters

  • The regulatory landscape controlling Hoxd gene expression in tetrapod digit development was probably co-opted from a pre-existing cloacal regulatory mechanism, as evidenced by the effects of genetic deletion experiments in zebrafish fin, cloaca and mouse urogenital development.

    • Aurélie Hintermann
    • Christopher C. Bolt
    • Denis Duboule
    ResearchOpen Access
    Nature
    Volume: 648, P: 109-116

  • Temporal activation of Hox genes in mouse pseudo-embryos in vitro initiates at the anterior part of the cluster and is accompanied by asymmetric loading of cohesin. Posterior CTCF sites then successively act as transient insulators, regulating the timed transcription of more posterior-located genes.

    • Hocine Rekaik
    • Lucille Lopez-Delisle
    • Denis Duboule
    ResearchOpen Access
    Nature Genetics
    Volume: 55, P: 1164-1175

  • Here the authors show that a strong enhancer sequence can be controlled by the chromatin environment provided by a topologically associated domain (TAD) located nearby. An enhancer relocated by homologous recombination takes all the hallmarks of its new neighboring enhancers located in the recipient TAD.

    • Christopher Chase Bolt
    • Lucille Lopez-Delisle
    • Denis Duboule
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15