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Showing 1–2 of 2 results
Advanced filters: Author: Auriane Rakitch Clear advanced filters

  • How RNA folds into functional structures is still largely uncharacterized. Here, using cryo-EM, SAXS, and molecular dynamics (MD) simulations, the authors create a movie of a medically relevant ribozyme acquiring its functionally active conformation.

    • Shekhar Jadhav
    • Mauro Maiorca
    • Marco Marcia
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19

  • Unwanted RNA transcripts are targeted for degradation by nuclear complexes such as MTREC/PAXT. Here, the authors structurally and functionally characterized three interfaces of the scaffold protein Red1, providing mechanistic insights into conserved features of MTREC/PAXT architecture.

    • Anne-Emmanuelle Foucher
    • Leila Touat-Todeschini
    • Jan Kadlec
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17