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Showing 1–2 of 2 results
Advanced filters: Author: Avery Feit Clear advanced filters

  • Sequencing analysis of tamoxifen-associated uterine cancers and further in vivo analyses suggest that the drug tamoxifen can activate the PI3K pathway in the absence of oncogenic mutations.

    • Kirsten Kübler
    • Agostina Nardone
    • Rinath Jeselsohn
    ResearchOpen Access
    Nature Genetics
    Volume: 57, P: 2192-2202

  • The role of MYC in transcriptional reprogramming in prostate cancer remains poorly characterized. Here, MYC overexpression antagonizes the canonical AR transcriptional program leading to prostate tumor initiation and progression by disrupting transcriptional pause release at AR-regulated genes.

    • Xintao Qiu
    • Nadia Boufaied
    • David P. Labbé
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-17