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Showing 1–18 of 18 results
Advanced filters: Author: Avi Schroeder Clear advanced filters

  • Delivering immunomodulatory compounds to myeloid cells can activate innate immunity for cancer immunotherapy. Here the authors design a polymersome-based nanocarrier for delivering β-glucan to red pulp myeloid cells in the spleen and show that their strategy achieves tumour growth reduction in a melanoma model.

    • Annelies C. Wauters
    • Jari F. Scheerstra
    • Jan C. M. van Hest
    ResearchOpen Access
    Nature Nanotechnology
    Volume: 19, P: 1735-1744

  • A high-throughput nanoscale 3D microscopy technique, combining imaging flow cytometry with a point-spread function, allows 3D localization measurements in live flowing cells.

    • Lucien E. Weiss
    • Yael Shalev Ezra
    • Yoav Shechtman
    Research
    Nature Nanotechnology
    Volume: 15, P: 500-506

  • Determining the most effective treatment for each cancer patient is a key challenge in cancer therapy. In this article, the authors show, in a mouse model of breast cancer, that DNA barcoded nanoparticles can be used for pre-screening the efficacy of anticancer drugs.

    • Zvi Yaari
    • Dana da Silva
    • Avi Schroeder
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-10

  • Synthetic biology and engineering approaches are harnessed to incorporate new capabilities in synthetic cells. Here, the authors designed bioluminescent signaling mechanisms for intracellular and intercellular synthetic-to-natural cell communication.

    • Omer Adir
    • Mia R. Albalak
    • Avi Schroeder
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • Metastasis remains difficult to treat owing to the heterogeneity of metastatic cancer cells and the various dynamic steps of the metastatic cascade. This Review discusses the design of nanomedicines for the specific treatment of metastasis.

    • Roger M. Pallares
    • Lorena Consolino
    • Twan Lammers
    Reviews
    Nature Reviews Bioengineering
    Volume: 4, P: 47-66

  • COVID-19, similarly to systemic autoimmune diseases, is characterised by the presence of autoantibodies. Authors show here that the abundance and network signature of autoantibodies targeting G protein-coupled receptors and RAS-related proteins are altered in COVID-19 patients, and the level of disruption marks clinical severity.

    • Otavio Cabral-Marques
    • Gilad Halpert
    • Yehuda Shoenfeld
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12

  • Metastasis accounts for the vast majority of cancer deaths. The potential of using nanoparticles to diagnose and to treat metastatic cancer is highlighted in this Review.

    • Avi Schroeder
    • Daniel A. Heller
    • Daniel G. Anderson
    Reviews
    Nature Reviews Cancer
    Volume: 12, P: 39-50

  • Dror et al. report that melanoma-derived melanosomes carry miRNAs that induce primary fibroblast reprogramming into cancer-associated fibroblasts, and also induce the formation of a pro-tumorigenic niche.

    • Shani Dror
    • Laureen Sander
    • Carmit Levy
    Research
    Nature Cell Biology
    Volume: 18, P: 1006-1017

  • Nanotechnology-based antimicrobial and antiviral formulations can prevent SARS-CoV-2 viral dissemination, and highly sensitive biosensors and detection platforms may contribute to the detection and diagnosis of COVID-19.

    • Sepehr Talebian
    • Gordon G. Wallace
    • João Conde
    Comments & Opinion
    Nature Nanotechnology
    Volume: 15, P: 618-621

  • Developing vaccines for glioblastoma remains challenging owing to the immunosuppressive microenvironment of the tumour and the presence of the blood–brain barrier. In this Perspective, we explore how nanomaterials can be tailored to address the limitations of glioblastoma vaccination, potentially paving the way for important advancements.

    • Fatima Hameedat
    • Bárbara B. Mendes
    • Flávia Sousa
    Reviews
    Nature Reviews Materials
    Volume: 9, P: 628-642

  • The authors propose a framework to be followed during preclinical investigation of nanomedicines to increase their translatability potential.

    • Paul Joyce
    • Christine J. Allen
    • Hélder A. Santos
    Reviews
    Nature Nanotechnology
    Volume: 19, P: 1597-1611

  • In this Primer, Conde and colleagues explain how to design smart nucleic acid delivery methods, which provide functionality and efficacy in the layout of molecular diagnostics and therapeutic systems.

    • Bárbara B. Mendes
    • João Conniot
    • João Conde
    Reviews
    Nature Reviews Methods Primers
    Volume: 2, P: 1-21

  • Tissue cytometry is a promising new microscopy technique that can be used to enumerate and characterize each cell in a tissue. Here the authors describe a complete and accessible pipeline, including methods of sample preparation, microscopy, image analysis, and data analysis for large-scale three-dimensional tissue cytometry of human kidney tissues.

    • Michael J. Ferkowicz
    • Seth Winfree
    • Francis Perry Wilson
    Research
    Laboratory Investigation
    Volume: 101, P: 661-676