Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: Avraham Shakked Clear advanced filters

  • Shakked et al. highlight the importance of cardiomyocytes’ redifferentiation after dedifferentiation and proliferation in cardiac repair and show that redifferentiation depends on negative feedback signaling and LATS1/2 Hippo pathway activity. Cardiomyocyte redifferentiation not only promotes the restoration of cardiac function but also protects against future insult.

    • Avraham Shakked
    • Zachary Petrover
    • Eldad Tzahor
    Research
    Nature Cardiovascular Research
    Volume: 2, P: 383-398

  • Aharonov et al. use in vivo genetic approaches to show that ErBB2-mediated YAP activation initiates epithelial–mesenchymal transition-like processes and dedifferentiation of cardiomyocytes to drive heart regeneration.

    • Alla Aharonov
    • Avraham Shakked
    • Eldad Tzahor
    Research
    Nature Cell Biology
    Volume: 22, P: 1346-1356

  • Zhang et al. show that Egr1 regulates transient senescence during neonatal heart regeneration and upon agrin-mediated cardiac repair in adult mice, acting downstream of the integrin–FAK–ERK–Akt1 axis in cardiac fibroblasts.

    • Lingling Zhang
    • Jacob Elkahal
    • Eldad Tzahor
    Research
    Nature Cardiovascular Research
    Volume: 3, P: 915-932

  • Although Hippo signaling restricts regeneration in many mammalian organs, the pharmaceutical tools available to modulate the pathway have been limited. Here, the authors report a small molecule that may inhibit a key element in the Hippo cascade and may activate regenerative responses in several mammalian tissues.

    • Nathaniel Kastan
    • Ksenia Gnedeva
    • A. J. Hudspeth
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12