Liquid-crystal gel networks of neurofilament assemblies play a key part in the mechanical stability of neuronal processes, and disruptions in the networks are a hallmark of motor-neuron diseases. Under pressure, these networks are shown to undergo an abrupt transition from expanded to condensed states, with distinct mechanical properties, helping to explain possible disruption mechanisms.
- Roy Beck
- Joanna Deek
- Cyrus R. Safinya
