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Showing 1–4 of 4 results
Advanced filters: Author: Backialakshmi Dharmalingam Clear advanced filters

  • Mohanakrishnan et al. identify a distinct subset of post-arterial capillaries, termed type R. They show that type R capillaries contribute to trabecular bone formation in the diaphysis and respond to anti-osteoporosis treatments.

    • Vishal Mohanakrishnan
    • Kishor K. Sivaraj
    • Ralf H. Adams
    ResearchOpen Access
    Nature Cell Biology
    Volume: 26, P: 2020-2034

  • Sivaraj, Majev et al. demonstrate that the inactivation of Lats2 in endothelial cells triggers the upregulation of serum response factor and endothelial-to-mesenchymal transition, leading to myofibroblast formation, bone marrow fibrosis, osteosclerosis, impaired bone marrow function and extramedullary hematopoiesis.

    • Kishor K. Sivaraj
    • Paul-Georg Majev
    • Ralf H. Adams
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 3, P: 951-969

  • Developmental and regenerative bone formation require the removal of chondrocytes and matrix. Here the authors show that these processes involve mesenchymal stromal cell-derived septoclasts, which disappear after the completion of development but re-emerge during fracture healing.

    • Kishor K. Sivaraj
    • Paul-Georg Majev
    • Ralf H. Adams
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16