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Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection

Variation in antibody levels elicited by the COVID-19 vaccine ChAdOx1 nCov-19 is linked to specific major histocompatibility complex class II alleles, providing insight into the breadth of immune response among vaccinated individuals.

Alexander J. Mentzer
Daniel O’Connor
Julian C. Knight
ResearchOpen Access13 Oct 2022
Nature Medicine

Volume: 29, P: 147-157

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Human leukocyte antigen alleles associate with COVID-19 vaccine immunogenicity and risk of breakthrough infection

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