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Showing 1–5 of 5 results
Advanced filters: Author: Baokun Gu Clear advanced filters

  • The metabolic environment of tumours has wide-ranging effects on the anti-tumour immune response and the outcome of immune therapy. Authors show here that the purine metabolite inosine enhances tumour immunogenicity and thus immune checkpoint blockade therapy response by inhibiting the ubiquitin-activating enzyme UBA6 in tumour cells.

    • Lei Zhang
    • Li Jiang
    • Baokun He
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16

  • Using electrostatic doping, the real and imaginary parts of the refractive index along the extraordinary axis of semiconducting, highly aligned, single-walled carbon nanotubes over 4″ wafers can be tuned by up to 5.9% and 14.3% in the infrared at 2,200 nm and 1,660 nm, respectively.

    • Jason Lynch
    • Evan Smith
    • Deep Jariwala
    Research
    Nature Photonics
    Volume: 18, P: 1176-1184

  • Gate-tunable heterojunction diodes—or triodes—that are based on van der Waals heterostructures formed from two-dimensional indium selenide and three-dimensional silicon can exhibit subthreshold slopes of 6.4 mV decade–1 and on-state current densities of 0.3 µA µm–1 at a drain bias of –1 V.

    • Jinshui Miao
    • Chloe Leblanc
    • Deep Jariwala
    Research
    Nature Electronics
    Volume: 5, P: 744-751

  • Through structure-guided protein engineering, Guo et al. developed a Lachnospiraceae bacterium Cas12a variant with enhanced editing efficiency and applied the enzyme-dead version of this variant for multiplex gene activation in the mouse retina.

    • Lucie Y. Guo
    • Jing Bian
    • Lei S. Qi
    Research
    Nature Cell Biology
    Volume: 24, P: 590-600