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Showing 1–4 of 4 results
Advanced filters: Author: Barbara True-Driver Clear advanced filters

  • Genomic analysis of 551 esophageal adenocarcinomas identifies new driver mutations and biomarkers associated with poor prognosis. More than 50% of esophageal adenocarcinomas contain sensitizing events for CDK4/CDK6 inhibitors, thus providing an evidence base for targeted therapeutics.

    • Alexander M. Frankell
    • SriGanesh Jammula
    • Rebecca C. Fitzgerald
    Research
    Nature Genetics
    Volume: 51, P: 506-516

  • Dark matter searches have faced challenges in detecting lighter particles with traditional xenon detectors. The authors propose the HydroX concept, integrating hydrogen into liquid xenon detectors, enhancing sensitivity to lighter dark matter particles and detection capabilities in the field.

    • W. H. Lippincott
    • H. N. Nelson
    • T. Zhang
    ResearchOpen Access
    Communications Physics
    Volume: 8, P: 1-8

  • Joana Carlevaro-Fita, Andrés Lanzós et al. present the Cancer LncRNA Census (CLC), a manually curated dataset of 122 long noncoding RNAs (lncRNAs) with experimentally-validated functions in cancer based on data from the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. CLC lncRNAs have unique gene features, and a number display evidence for cancer-driving functions that are conserved from humans to mice.

    • Joana Carlevaro-Fita
    • Andrés Lanzós
    • Christian von Mering
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-16