Nature Search

Multivariate genome-wide analyses of the well-being spectrum

New methods for multivariate genome-wide-association meta-analysis (GWAMA) applied to four well-being spectrum traits identifies 304 association loci, representing a 26% increase in the number of signals, as compared with four univariate analyses.

Bart M. L. Baselmans
Rick Jansen
Meike Bartels
Research14 Jan 2019
Nature Genetics

Volume: 51, P: 445-451
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Daniel Benjamin, Meike Bartels, Philipp Koellinger and colleagues report a genome-wide association meta-analysis of subjective well-being, depressive symptoms and neuroticism. The study leverages a large sample size together with genetic correlations between the phenotypes to identify, with high confidence, loci associated with each phenotype.

Aysu Okbay
Bart M L Baselmans
David Cesarini
Research18 Apr 2016
Nature Genetics

Volume: 48, P: 624-633
GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability

A GWAS of lifetime cannabis use reveals new risk loci, shows that cannabis use has genetic overlap with smoking and alcohol use, and indicates that the likelihood of initiating cannabis use is causally influenced by schizophrenia.

Joëlle A. Pasman
Karin J. H. Verweij
Jacqueline M. Vink
Research27 Aug 2018
Nature Neuroscience

Volume: 21, P: 1161-1170
Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability

Joëlle A. Pasman
Karin J. H. Verweij
Jacqueline M. Vink
Amendments and Corrections05 Jun 2019
Nature Neuroscience

Volume: 22, P: 1196
Correction: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Aysu Okbay
Bart M L Baselmans
David Cesarini
Amendments and Corrections29 Nov 2016
Nature Genetics

Volume: 48, P: 1591
Correction: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Aysu Okbay
Bart M L Baselmans
David Cesarini
Amendments and Corrections27 Jul 2016
Nature Genetics

Volume: 48, P: 970
Expanding the environmental scope: an environment-wide association study for mental well-being

Margot P. van de Weijer
Bart M. L. Baselmans
Meike Bartels
ResearchOpen Access14 Jun 2021
Journal of Exposure Science & Environmental Epidemiology

Volume: 32, P: 195-204
DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

Jenny van Dongen
Fiona A. Hagenbeek
Dorret I. Boomsma
ResearchOpen Access08 Jan 2021
Molecular Psychiatry

Volume: 26, P: 2148-2162
Biological insights into multiple birth: genetic findings from UK Biobank

Hamdi Mbarek
Margot P. van de Weijer
Dorret I. Boomsma
Research13 Feb 2019
European Journal of Human Genetics

Volume: 27, P: 970-979

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