Neuropixels Opto probes combine high-density recording sites with optical waveguide-based light emission sites for simultaneous recording of neuronal activity and optogenetic stimulation with blue and/or red light. As demonstrated in the mouse brain, these probes allow the activation or silencing of defined groups of neurons while acquiring high-quality recordings.
- Anna A. Lakunina
- Karolina Z. Socha
- Matteo Carandini