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Showing 1–2 of 2 results
Advanced filters: Author: Bassem Al-Sady Clear advanced filters

  • Marin et al. report the role of lamin proteins and the lamin B receptor (LBR) in chromatin positioning at the nuclear periphery. Knockout of all lamins and LBR in mouse embryonic stem cells leads to heterochromatin detachment and derepression of gene and transposon expression.

    • Harold C. Marin
    • Charlie Allen
    • Abigail Buchwalter
    ResearchOpen Access
    Nature Cell Biology
    Volume: 27, P: 1311-1326

  • Protein abundance is controlled at the transcriptional, translational and posttranslational levels. Here, Öztürk et al. determine proteome changes resulting from individual knockout of 3308 nonessential genes in the yeast S. pombe, infer gene functionality, and show that protein upregulation under stable transcript expression utilizes optimal codons.

    • Merve Öztürk
    • Anja Freiwald
    • Falk Butter
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10