Bastián-Eugenio et al. showed that calcium entering the cell via TRPV1, but not P2X4 channels, can induce calcium-dependent inactivation of Orai1. This inactivation impacts thrombin-induced cell migration and wound healing suggesting an important role of Orai1 modulation by TRPV1 channels.
- Carlos Ernesto Bastián-Eugenio
- Arlette Bohórquez-Hernández
- Luis Vaca