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Showing 1–7 of 7 results
Advanced filters: Author: Beata Jablonska Clear advanced filters
  • Jablonska et al. find that adult mouse neural progenitors can markedly alter their fate, from olfactory bulb interneurons to oligodendroglia, in response to demyelination. The fate change is triggered by chordin, which is upregulated in the subventricular zone in this pathological condition.

    • Beata Jablonska
    • Adan Aguirre
    • Vittorio Gallo
    Research
    Nature Neuroscience
    Volume: 13, P: 541-550
  • Oligodendrocyte progenitor cell (OPC) proliferation is crucial for regeneration after hypoxic lesions in mice, a model of diffuse white matter injury of premature infants. Here, the authors show that the histone deacetylase Sirt1 is a Cdk2-dependent mediator of OPC proliferation and OPC response to hypoxia.

    • Beata Jablonska
    • Marcin Gierdalski
    • Vittorio Gallo
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-16
  • Hypoxic brain damage associated with premature birth causes lasting neurological impairments. Here, the authors use environmental enrichment to rescue white matter dysmaturation following hypoxia, while identifying a critical window of intervention and oligodendrocyte-specific changes in gene expression.

    • Thomas A. Forbes
    • Evan Z. Goldstein
    • Vittorio Gallo
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-17
  • Diffuse white matter injury is common in very preterm infants; here, enhanced epidermal growth factor receptor signalling in oligodendrocyte precursor cells in a mouse model of such injury is shown to increase cellular and functional recovery.

    • Joseph Scafidi
    • Timothy R. Hammond
    • Vittorio Gallo
    Research
    Nature
    Volume: 506, P: 230-234
  • In this Perspective, the authors review the literature and suggest that the cognitive pathology that often accompanies preterm birth and/or very low birth weight may be a direct result of perinatal hypoxia that, in turn, leads to perturbations in the maturation and development of interneurons, oligodendrocytes and astrocytes.

    • Natalina Salmaso
    • Beata Jablonska
    • Vittorio Gallo
    Reviews
    Nature Neuroscience
    Volume: 17, P: 341-346