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Showing 1–7 of 7 results

Advanced filters: Author: Beatrice Pinna Clear advanced filters

RFX transcription factors are essential for hearing in mice

Inner ear hair cells are non-regenerative mechanosensory cells essential for hearing. Here, with cell-type-specific expression analyses, the authors identify RFX transcription factors as central mediators of their survival during terminal differentiation and thus essential for hearing in mice.

Ran Elkon
Beatrice Milon
Ronna Hertzano
ResearchOpen Access15 Oct 2015
Nature Communications

Volume: 6, P: 1-14
Helios is a key transcriptional regulator of outer hair cell maturation

Ikzf2, which encodes the transcription factor Helios, is identified as a crucial regulator of gene expression in maturing cochlear outer hair cells, and overexpression of Ikzf2 in inner hair cells induces prestin expression and electromotility.

Lauren Chessum
Maggie S. Matern
Ronna Hertzano
Research21 Nov 2018
Nature

Volume: 563, P: 696-700
Gfi1^Cre mice have early onset progressive hearing loss and induce recombination in numerous inner ear non-hair cells

Maggie Matern
Sarath Vijayakumar
Ronna Hertzano
ResearchOpen Access09 Feb 2017
Scientific Reports

Volume: 7, P: 1-13
Cortical mechanisms of spatial hearing

Humans and other animals use spatial hearing to rapidly localize events in the environment. Here, van der Heijden and colleagues discuss the latest insights from neurophysiological, neuroimaging and computational modelling studies into the cortical encoding of sound location.

Kiki van der Heijden
Josef P. Rauschecker
Elia Formisano
Reviews29 Aug 2019
Nature Reviews Neuroscience

Volume: 20, P: 609-623
Short-term NAD⁺ supplementation prevents hearing loss in mouse models of Cockayne syndrome

Mustafa N. Okur
Beatrice Mao
Vilhelm A. Bohr
ResearchOpen Access07 Jan 2020
npj Aging and Mechanisms of Disease

Volume: 6, P: 1-10
A same day α-synuclein RT-QuIC seed amplification assay for synucleinopathy biospecimens

Sabiha Parveen
Parvez Alam
Byron Caughey
ResearchOpen Access11 Feb 2025
npj Biosensing

Volume: 2, P: 1-9
Polyol pathway-generated fructose is indispensable for growth and survival of non-small cell lung cancer

Annemarie Schwab
Mohammad Aarif Siddiqui
Paolo Ceppi
ResearchOpen Access20 Nov 2024
Cell Death & Differentiation

Volume: 32, P: 587-597