After spinal cord injury (SCI), cyclic adenosine monophosphate (cAMP) levels drop in the central nervous system. Here, authors show that boosting cAMP and subsequently activating corticospinal neurons led to improved neuronal function and motor recovery in female rats after SCI, highlighting a brainstem rerouting pathway for restoring movement after injury.
- Beatriz Martínez-Rojas
- Samuel Martín-Pérez
- Victoria Moreno-Manzano
