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Showing 1–7 of 7 results
Advanced filters: Author: Ben Berkhout Clear advanced filters
  • Initiating antiretroviral therapy (ART) during primary HIV-1 infection (PHI) may influence long-term viral persistence, yet its enduring effects remain unclear. Here, Pasternak and colleagues demonstrate that temporary ART started early in infection reduces HIV-1 proviral diversity and monocyte activation, and sustains lower levels of viral persistence markers, suggesting a lasting suppressive impact on the HIV-1 reservoir.

    • Alexander O. Pasternak
    • Pien M. van Paassen
    • Ben Berkhout
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16
  • The development of effective antiretroviral therapies has greatly improved the disease prognosis for patients with HIV. However, the limitations of these therapies have renewed interest in developing alternative treatment strategies. Here, a group of experts from the International AIDS Society discuss the research steps that need to be taken to achieve the ultimate objective — a cure for HIV.

    • Steven G. Deeks
    • Brigitte Autran
    • Françoise Barré-Sinoussi
    Reviews
    Nature Reviews Immunology
    Volume: 12, P: 607-614
  • The Deep Decarbonization Pathways Project develops a framework to design low-emission development pathways. This Perspective discusses the framework and how it can support the development of national strategies to meet climate targets, as well as help achieve stakeholder engagement.

    • Henri Waisman
    • Chris Bataille
    • Hilton Trollip
    Reviews
    Nature Climate Change
    Volume: 9, P: 261-268
  • Schouls et al. characterize antimicrobial resistance genes in MRSA isolates from humans and livestock in the Netherlands. The multidrug resistance gene cfr and the phenicol resistance gene fexA are identified in both types of samples, including in samples taken from persons having professional contact with livestock.

    • Leo M. Schouls
    • Kees Veldman
    • H. Berkhout
    ResearchOpen Access
    Communications Medicine
    Volume: 2, P: 1-13