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Showing 1–3 of 3 results
Advanced filters: Author: Benedikt Rossboth Clear advanced filters

  • Determining molecular clustering in Photoactivated Localization Microscopy (PALM) experiments requires knowledge of the blinking properties of the fluorophore to prevent overcounting artefacts. Here the authors develop an experimental and analytical framework to determine the blinking parameters of fluorophores and incorporate this information into cluster analysis.

    • René Platzer
    • Benedikt K. Rossboth
    • Mario Brameshuber
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Higher-order TCRs have been postulated to maintain high antigen sensitivity and trigger signaling. Huppa and colleagues use various investigative techniques and find exclusively monomeric TCR–CD3 complexes that drive the recognition of antigenic pMHC.

    • Mario Brameshuber
    • Florian Kellner
    • Johannes B. Huppa
    Research
    Nature Immunology
    Volume: 19, P: 487-496