Nature Search

Generic self-stabilization mechanism for biomolecular adhesions under load

Cellular adhesions have the remarkable property that they adapt their stability to the applied mechanical load. Here, authors describe a generic physical mechanism that explains self-stabilization of idealized adhesion systems under shear.

Andrea Braeutigam
Ahmet Nihat Simsek
Benedikt Sabass
ResearchOpen Access22 Apr 2022
Nature Communications

Volume: 13, P: 1-9
Author Correction: Sparse inference and active learning of stochastic differential equations from data

Yunfei Huang
Youssef Mabrouk
Benedikt Sabass
Amendments and CorrectionsOpen Access29 Mar 2024
Scientific Reports

Volume: 14, P: 1
Verticalization of bacterial biofilms

Biofilms of rod-shaped bacteria can grow from a two-dimensional layer of founder cells into a three-dimensional structure with a vertically aligned core. Here, the physics underlying this transition is traced down to the properties of individual cells.

Farzan Beroz
Jing Yan
Ned S. Wingreen
Research18 Jun 2018
Nature Physics

Volume: 14, P: 954-960
Multiplexing molecular tension sensors reveals piconewton force gradient across talin-1

A genetically encoded tension sensor module for measuring molecular forces at 3–5 pN along with tools for multiplexed tension sensing and data analysis reveal an intramolecular tension gradient across talin-1 during cell adhesion.

Pia Ringer
Andreas Weißl
Carsten Grashoff
Research18 Sept 2017
Nature Methods

Volume: 14, P: 1090-1096
Non-equilibrium dynamics of bacterial colonies—growth, active fluctuations, segregation, adhesion, and invasion

Adhesion forces due to active pili govern the formation of biofilms by a wide range of bacteria. Using simulations, this work shows how such active adhesions determine the morphology of bacterial collectives, their non-equilibrium fluctuations, and the spreading dynamics in different geometries.

Kai Zhou
Marc Hennes
Benedikt Sabass
ResearchOpen Access12 Oct 2022
Communications Physics

Volume: 5, P: 1-13
Sparse inference and active learning of stochastic differential equations from data

Yunfei Huang
Youssef Mabrouk
Benedikt Sabass
ResearchOpen Access15 Dec 2022
Scientific Reports

Volume: 12, P: 1-17
Traction force microscopy with optimized regularization and automated Bayesian parameter selection for comparing cells

Yunfei Huang
Christoph Schell
Benedikt Sabass
ResearchOpen Access24 Jan 2019
Scientific Reports

Volume: 9, P: 1-16
Extracellular rigidity sensing by talin isoform-specific mechanical linkages

Austen et al. generated talin biosensors to study integrin-based force transduction. They report that extracellular rigidity sensing requires talin’s mechanical engagement and find talin isoform-dependent effects in integrin-mediated mechanosensing.

Katharina Austen
Pia Ringer
Carsten Grashoff
Research02 Nov 2015
Nature Cell Biology

Volume: 17, P: 1597-1606

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