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Advanced filters: Author: Benjamin D. Senzer Clear advanced filters

  • A CRISPR–Cas9 screening-based structure–activity relationship profiling method reveals that LSD1 inhibitors suppress acute myeloid leukemia by disruption of the interaction between LSD1 and GFI1B instead of the enzyme activity of LSD1.

    • Michael E. Vinyard
    • Cindy Su
    • Brian B. Liau
    Research
    Nature Chemical Biology
    Volume: 15, P: 529-539