The RNA-binding protein SRSF7 autoregulates its protein levels through an intricate negative feedback mechanism that involves translation of two distinct protein halves, termed Split-ORFs; the potential to encode Split-ORFs is also seen in other targets of nonsense-mediated decay.
- Vanessa Königs
- Camila de Oliveira Freitas Machado
- Michaela Müller-McNicoll
