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Long non-coding RNAs as a biomarker for homologous recombination deficiency and parp inhibitor sensitivity in high-grade serous ovarian cancers

Long non-coding RNAs are identified as non-invasive biomarkers predicting homologous recombination deficiency and PARP inhibitor sensitivity in high-grade serous ovarian cancer, enabling improved precision oncology approaches.

Kai Doberstein
Johannes Panther
Frederik Marmé
ResearchOpen Access01 Oct 2025
Communications Biology

Volume: 8, P: 1-17

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Long non-coding RNAs as a biomarker for homologous recombination deficiency and parp inhibitor sensitivity in high-grade serous ovarian cancers

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