Hantaan virus is a lifethreatening Bunyavirus. Here the authors determine the cryoelectron microscopy structure of its polymerase, a central enzyme involved in viral genome replication. Structures combined with in vitro activity decipher at high resolution the molecular mechanisms of the replication cycle.
- Quentin Durieux Trouilleton
- Sergio Barata-García
- Hélène Malet
