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Natural RNA circles function as efficient microRNA sponges

A natural circular RNA termed ciRS-7 is shown to function as a negative regulator of microRNA; ciRS-7 acts as an efficient sponge for the microRNA miR-7, and is resistant to the usual microRNA-mediated degradation pathway of exonucleolytic RNA decay.

Thomas B. Hansen
Trine I. Jensen
Jørgen Kjems
Research27 Feb 2013
Nature

Volume: 495, P: 384-388
Plasma Escherichia Coli β-Galactosidase as a Marker of Tumor Burden and Response to Experimental Anti-Neoplastic Therapy in Nude Mice Xenografted with lacZ Transduced Human Tumor Cells

Claus Holst-Hansen
Ross Wentworth Stephens
Nils Brünner
Research01 May 2000
Laboratory Investigation

Volume: 80, P: 719-724
Testosterone exacerbates neutrophilia and cardiac injury in myocardial infarction via actions in bone marrow

Men develop larger myocardial infarction (MI) sizes than women. Here, the authors show that male sex and testosterone, via bone marrow stroma, exacerbates MI-induced neutrophilia and cardiac injury and that response to anti-inflammatory treatment in MI is greater in men than women

Elin Svedlund Eriksson
Marta Lantero Rodriguez
Åsa Tivesten
ResearchOpen Access05 Feb 2025
Nature Communications

Volume: 16, P: 1-16
Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes

Christian Rungsted Andersson
Jeppe Falsig
Jan Torleif Pedersen
ResearchOpen Access15 Mar 2019
Scientific Reports

Volume: 9, P: 1-12
Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease

Athanasios Metaxas
Camilla Thygesen
Bente Finsen
ResearchOpen Access31 Oct 2019
Scientific Reports

Volume: 9, P: 1-15
Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling

Bettina Hjelm Clausen
Matilda Degn
Kate Lykke Lambertsen
ResearchOpen Access07 Jul 2016
Scientific Reports

Volume: 6, P: 1-16
Clinical impact of clonal hematopoiesis in patients with lymphoma undergoing ASCT: a national population-based cohort study

Simon Husby
Francesco Favero
Kirsten Grønbæk
Research20 Mar 2020
Leukemia

Volume: 34, P: 3256-3268

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Natural RNA circles function as efficient microRNA sponges

Plasma Escherichia Coli β-Galactosidase as a Marker of Tumor Burden and Response to Experimental Anti-Neoplastic Therapy in Nude Mice Xenografted with lacZ Transduced Human Tumor Cells

Testosterone exacerbates neutrophilia and cardiac injury in myocardial infarction via actions in bone marrow

Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease

Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling

Clinical impact of clonal hematopoiesis in patients with lymphoma undergoing ASCT: a national population-based cohort study

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