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Showing 1–6 of 6 results
Advanced filters: Author: Beum-Chang Kang Clear advanced filters

  • Split DddA-derived base editors fused to TALEs enable mitochondrial DNA editing. Here the authors demonstrate their use in mouse embryos with germline transmission.

    • Hyunji Lee
    • Seonghyun Lee
    • Jin-Soo Kim
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-6

  • Cpf1 is a type V CRISPR effector protein that has different target and guide RNA requirements compared to Cas9, thus offering an addition tool for precision genome editing. Here Kimet al. show that Cpf1 ribonucleoprotein can be introduced into protoplasts and used for transgene-free gene editing in plants.

    • Hyeran Kim
    • Sang-Tae Kim
    • Sang-Gyu Kim
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-7

  • This study showed efficient base editing of mitochondria and chloroplast genomes in both lettuce and rapeseed by DddA-derived cytosine base editors (DdCBEs), and DNA-free editing in chloroplasts by delivering DdCBE mRNA to protoplasts, which avoids off-target effects.

    • Beum-Chang Kang
    • Su-Ji Bae
    • Jin-Soo Kim
    ResearchOpen Access
    Nature Plants
    Volume: 7, P: 899-905

  • Plant-compatible adenine base editor systems are now demonstrated to work in protoplasts and individual plants of Arabidopsis thaliana and Brassica napus, yielding plants with predicted nucleotide substitutions and stably inherited phenotypes.

    • Beum-Chang Kang
    • Jae-Young Yun
    • Jin-Soo Kim
    Research
    Nature Plants
    Volume: 4, P: 427-431