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Showing 1–6 of 6 results
Advanced filters: Author: Bianca Weinstock-Guttman Clear advanced filters

  • Multiple sclerosis research in 2011 produced a combination of new therapeutic developments and innovative findings. Teriflunomide showed beneficial effects in a phase III trial, quantification methods for MRI lesions that should improve monitoring of disease progression were devised, and a link between high cholesterol and low vitamin D emerged.

    • Bianca Weinstock–Guttman
    • Murali Ramanathan
    News & Views
    Nature Reviews Neurology
    Volume: 8, P: 66-68

  • A randomized, double-blind, sham-controlled trial, Brave Dreams, has shown no clinical or radiological benefit of percutaneous transluminal angioplasty (PTA) to correct chronic cerebrospinal venous insufficiency in patients with multiple sclerosis (MS). These results finally settle the scientific debate over whether PTA can improve clinical, radiological and symptomatic outcomes in this patient population.

    • Robert Zivadinov
    • Bianca Weinstock-Guttman
    News & Views
    Nature Reviews Neurology
    Volume: 14, P: 129-130

  • Approximately half of the people currently with multiple sclerosis (MS) are ≥50 years of age, yet guidelines for management of MS in older age are lacking. This Consensus statement presents the outcomes of an International Advisory Committee on Clinical Trials (IACCT) in MS workshop on ageing and MS, including recommendations for advancing research, care and awareness.

    • Anneke van der Walt
    • Eva M. M. Strijbis
    • Yinan Zhang
    Reviews
    Nature Reviews Neurology
    Volume: 21, P: 432-448

  • Vaughn et al. review the challenges facing elderly patients with multiple sclerosis (MS). They describe the complex, evolving relationship between ageing and MS pathophysiology, highlight the lack of evidence for the safety and efficacy of disease-modifying therapies in elderly patients, and discuss treatment discontinuation and wellness strategies.

    • Caila B. Vaughn
    • Dejan Jakimovski
    • Bianca Weinstock-Guttman
    Reviews
    Nature Reviews Neurology
    Volume: 15, P: 329-342