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Scientific Reports (4)
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Showing 1–11 of 11 results

Advanced filters: Author: Biju Parekkadan Clear advanced filters

Erratum: Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure

Suraj J Patel
Jack M Milwid
Martin L Yarmush
Amendments and Corrections10 Mar 2014
Nature Biotechnology

Volume: 32, P: 291
Long-adapter single-strand oligonucleotide probes for the massively multiplexed cloning of kilobase genome regions

A library of single-strand oligonucleotide probes with a common long-adapter sequence can clone, in a single reaction, thousands of open reading frames spanning 400–5,000 bp, and has been applied to DNA from human stool and microbiome samples.

Lorenzo Tosi
Viswanadham Sridhara
Biju Parekkadan
Research26 Jun 2017
Nature Biomedical Engineering

Volume: 1, P: 1-9
Resolving cancer–stroma interfacial signalling and interventions with micropatterned tumour–stromal assays

Gene expression changes at the tumour–stroma interface are associated with epithelial cancer progression. Here, the authors describe a new in vitrosystem based on cell micropatterning and laser microdissection for examining the tumour–stromal interaction.

Keyue Shen
Samantha Luk
Biju Parekkadan
Research09 Dec 2014
Nature Communications

Volume: 5, P: 1-11
Suicide Gene-Engineered Stromal Cells Reveal a Dynamic Regulation of Cancer Metastasis

Keyue Shen
Samantha Luk
Biju Parekkadan
ResearchOpen Access19 Feb 2016
Scientific Reports

Volume: 6, P: 1-8
Ex vivo machine perfusion as a platform for lentiviral gene delivery in rat livers

Irina Filz von Reiterdank
Mohammadreza Mojoudi
Korkut Uygun
Research22 Apr 2025
Gene Therapy

Volume: 32, P: 421-429
Unbiased discovery of autoantibodies associated with severe COVID-19 via genome-scale self-assembled DNA-barcoded protein libraries

Pathogenic autoreactive antibodies associated with severe COVID-19 can be identified via self-assembled genome-scale libraries of full-length proteins covalently coupled to uniquely identifying DNA barcodes for analysis by sequencing.

Joel J. Credle
Jonathan Gunn
H. Benjamin Larman
Research19 Aug 2022
Nature Biomedical Engineering

Volume: 6, P: 992-1003
Biomanufacturing for clinically advanced cell therapies

This Review discusses the manufacturing of cell products for clinically advanced cell therapies, and highlights potential manufacturing bottlenecks and solutions towards the cost-effective commercialization of the therapies.

Ayesha Aijaz
Matthew Li
Biju Parekkadan
Reviews11 Jun 2018
Nature Biomedical Engineering

Volume: 2, P: 362-376
Therapeutic Delivery Specifications Identified Through Compartmental Analysis of a Mesenchymal Stromal Cell-Immune Reaction

Matthew Li
Danika Khong
Biju Parekkadan
ResearchOpen Access01 May 2018
Scientific Reports

Volume: 8, P: 1-12
Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure

Liver toxicity is one of the most common reasons for abandoning new drugs in development or withdrawing approved drugs from the market. Patel et al. show that in mice drug-induced liver injury can be limited by small-molecule inhibitor of the gap-junctional protein connexin 32.

Suraj J Patel
Jack M Milwid
Martin L Yarmush
Research15 Jan 2012
Nature Biotechnology

Volume: 30, P: 179-183
Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells

Ashley Allen
Natalie Vaninov
Rita N. Barcia
ResearchOpen Access23 Jun 2020
Scientific Reports

Volume: 10, P: 1-13
Author Correction: Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells

Ashley Allen
Natalie Vaninov
Rita N. Barcia
Amendments and CorrectionsOpen Access17 Sept 2020
Scientific Reports

Volume: 10, P: 1-2

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Erratum: Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure

Long-adapter single-strand oligonucleotide probes for the massively multiplexed cloning of kilobase genome regions

Resolving cancer–stroma interfacial signalling and interventions with micropatterned tumour–stromal assays

Suicide Gene-Engineered Stromal Cells Reveal a Dynamic Regulation of Cancer Metastasis

Ex vivo machine perfusion as a platform for lentiviral gene delivery in rat livers

Unbiased discovery of autoantibodies associated with severe COVID-19 via genome-scale self-assembled DNA-barcoded protein libraries

Biomanufacturing for clinically advanced cell therapies

Therapeutic Delivery Specifications Identified Through Compartmental Analysis of a Mesenchymal Stromal Cell-Immune Reaction

Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure

Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells

Author Correction: Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells

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