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Showing 1–3 of 3 results
Advanced filters: Author: Bikash C. Maity Clear advanced filters

  • The ability to evolve Plasmodium drug resistance in vitro is challenging and time consuming. Here, Kümpornsin et al. generated a Plasmodium falciparum parasite line with an elevated mutation rate by impairing the proof-reading activity of DNA polymerase, which results in a higher mutation rate, quick resistance development, and a lower inoculum than wild type to support the identification of new antimalarial targets and understand drug resistance mechanisms.

    • Krittikorn Kümpornsin
    • Theerarat Kochakarn
    • Marcus C. S. Lee
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • New antimalarials are urgently needed. Here, the authors identify Open Source Malaria compound, OSMS-106, as a reaction hijacking inhibitor of the malaria parasite protein synthesis machinery, with potential use for treatment and prophylaxis.

    • Stanley C. Xie
    • Yinuo Wang
    • Leann Tilley
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • Kagome materials have become a popular platform to investigate a range of competing quantum phases, such as the interplay between superconductivity and charge density waves (CDW). Here, the authors use x-ray diffraction, scanning tunneling microscopy and resonant elastic x-ray scattering to investigate the evolution of CDW ordering as a function of temperature in canted antiferromagnetic kagome FeGe. They find for post-annealed samples that the long-range CDW orders persist even as the structural modulations are suppressed although observations are highly dependent on the sample growth condition.

    • Chenfei Shi
    • Wenchang Hou
    • Jin-Ke Bao
    ResearchOpen Access
    Communications Physics
    Volume: 8, P: 1-10