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Showing 1–4 of 4 results
Advanced filters: Author: Billy W. Newton Clear advanced filters

  • Proteomic analysis coupled to RNA interference screening identifies the host exon–junction complex recycling factor partner of Y14 and mago (PYM1) as antiviral against three flaviruses, whose capsids interact with PYM1 and interfere with its ability to trigger nonsense-mediated decay-dependent degradation of viral RNA.

    • Minghua Li
    • Jeffrey R. Johnson
    • Holly Ramage
    Research
    Nature Microbiology
    Volume: 4, P: 985-995

  • The JWST MIRI transmission spectrum of WASP-107b, a transiting planet with Neptune-like mass and Jupiter-like radius, shows observations of sulfur dioxide and silicate clouds but no methane in its atmosphere, providing evidence of disequilibrium chemistry and active photochemistry.

    • Achrène Dyrek
    • Michiel Min
    • Gillian Wright
    Research
    Nature
    Volume: 625, P: 51-54

  • Using a multi-OMICS approach, Haas et al identify 54 human genes and 16 host-targeting chemical compounds that regulate influenza A virus infection in lung epithelial cells, including AHNAK and COBP1 which are also essential for SARS-CoV-2 infection.

    • Kelsey M. Haas
    • Michael J. McGregor
    • Nevan J. Krogan
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-27

  • AMBRA1 is the main regulator of the degradation of D-type cyclins, and loss of AMBRA1 promotes cell proliferation and tumour growth, and reduces the sensitivity of cancer cells to inhibition of CDK4 and CDK6.

    • Andrea C. Chaikovsky
    • Chuan Li
    • Julien Sage
    Research
    Nature
    Volume: 592, P: 794-798