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Showing 1–12 of 12 results

Advanced filters: Author: Bingrui Zhao Clear advanced filters

Decoding immunotherapy response through computational modeling

Multiomics data has revolutionized immuno-oncology studies by facilitating both populational and personalized facets of treatment planning. Here the authors review current computational tools, stratified into four ‘paradigms’, for analyzing multiomics data and facilitating optimization of cancer therapy.

Bingrui Li
Ruihan Luo
Xiaobo Zhou
ReviewsOpen Access15 Apr 2026
Nature Communications

P: 1-21
Single-cell transcriptomic landscape highlights epithelial-fibroblast interactions and CD44-mediated malignant traits in laryngeal squamous cell carcinoma

Meng Jin
Xin Wang
Yanan Sun
ResearchOpen Access18 Apr 2026
npj Precision Oncology

P: 1-18
Synaptic-like transmission between neural axons and arteriolar smooth muscle cells drives cerebral neurovascular coupling

In the CNS, glutamatergic neurons directly control functional hyperemia via synaptic-like transmission onto arteriolar smooth muscle cells. Inhibiting this process reduces brain atrophy following cerebral ischemia.

Dongdong Zhang
Jiayu Ruan
Jie-Min Jia
ResearchOpen Access02 Jan 2024
Nature Neuroscience

Volume: 27, P: 232-248
Prognostic Value of Tumor Heterogeneity on 18F-FDG PET/CT in HR+HER2− Metastatic Breast Cancer Patients receiving 500 mg Fulvestrant: a retrospective study

Yannan Zhao
Cheng Liu
Biyun Wang
ResearchOpen Access27 Sept 2018
Scientific Reports

Volume: 8, P: 1-7
Long non-coding RNA-dependent mechanism to regulate heme biosynthesis and erythrocyte development

LncRNAs modulate diverse physiological cellular processes, however, their involvement in heme-dependent processes are not yet clear. Here the authors reveal the role of lncRNA UCA1 in erythroid cell development.

Jinhua Liu
Yapu Li
Lihong Shi
ResearchOpen Access22 Oct 2018
Nature Communications

Volume: 9, P: 1-15
Single-cell transcriptomic analysis identifies an immune-prone population in erythroid precursors during human ontogenesis

Shi and colleagues describe a subset of erythroid precursors with immune characteristics that can be isolated from the yolk sac to the adult bone marrow stages during human ontogenesis.

Changlu Xu
Jian He
Lihong Shi
Research27 Jun 2022
Nature Immunology

Volume: 23, P: 1109-1120
A deep learning method based on multi-scale fusion for noise-resistant coal-gangue recognition

Qingjun Song
Shirong Sun
Haiyan Jiang
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-18
Prevalence and Abundance of Florfenicol and Linezolid Resistance Genes in Soils Adjacent to Swine Feedlots

Qin Zhao
Yang Wang
Jianzhong Shen
ResearchOpen Access30 Aug 2016
Scientific Reports

Volume: 6, P: 1-7
Cell-type deconvolution analysis identifies cancer-associated myofibroblast component as a poor prognostic factor in multiple cancer types

Bingrui Li
Guangsheng Pei
Zhongming Zhao
Research17 Jun 2021
Oncogene

Volume: 40, P: 4686-4694
Ca²⁺ oscillation in vascular smooth muscle cells control myogenic spontaneous vasomotion and counteract post-ischemic no-reflow

The no-reflow phenomenon after stroke is attributed to damaged spontaneous vasomotion of cerebral arterioles, which can be alleviated by maintaining mitochondria-ER contact-dependent Ca²⁺ oscillation.

Jinze Li
Yiyi Zhang
Jie-Min Jia
ResearchOpen Access15 Mar 2024
Communications Biology

Volume: 7, P: 1-21
Blocking GSDMD processing in innate immune cells but not in hepatocytes protects hepatic ischemia–reperfusion injury

Jichang Li
Jie Zhao
Xiaoni Kong
ResearchOpen Access17 Apr 2020
Cell Death & Disease

Volume: 11, P: 1-13
CCL5 deficiency promotes liver repair by improving inflammation resolution and liver regeneration through M2 macrophage polarization

Meng Li
Xuehua Sun
Qiang Xia
Research03 Sept 2019
Cellular & Molecular Immunology

Volume: 17, P: 753-764