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K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration

The authors show that K-ATP channels in dopamine (DA) neurons of the medial substantia nigra (m-SN) enable burst firing in vitro and in vivo. Silencing K-ATP channel activity in m-SN DA neurons decreases novelty-dependent exploratory behavior in mice.

Julia Schiemann
Falk Schlaudraff
Jochen Roeper
Research19 Aug 2012
Nature Neuroscience

Volume: 15, P: 1272-1280
Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells

The improper timing of transforming growth factor-β production is a hallmark of severe COVID-19 that may impede natural killer cell function and early control of infection.

Mario Witkowski
Caroline Tizian
Andreas Diefenbach
Research25 Oct 2021
Nature

Volume: 600, P: 295-301
Alleviation of migraine symptoms by application of repetitive peripheral magnetic stimulation to myofascial trigger points of neck and shoulder muscles – A randomized trial

Tabea Renner
Nico Sollmann
Mirjam N. Landgraf
ResearchOpen Access06 Apr 2020
Scientific Reports

Volume: 10, P: 1-11