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Hypothalamic CART is a new anorectic peptide regulated by leptin

Peter Kristensen
Martin E. Judge
Sven Hastrup
Research07 May 1998
Nature

Volume: 393, P: 72-76
CD8⁺ T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens

Autoreactive T cells are suspected to destroy hypocretin-producing neurons in narcolepsy. Here the authors detect CD8 T cells recognizing narcolepsy-related proteins in healthy individuals and in patients with narcolepsy, and show that the frequency of self-reactive CD8 T cells differs between patients and controls sharing the same HLA-II risk allele.

Natasja Wulff Pedersen
Anja Holm
Birgitte Rahbek Kornum
ResearchOpen Access19 Feb 2019
Nature Communications

Volume: 10, P: 1-12
Analytic framework for peptidomics applied to large-scale neuropeptide identification

Neuropeptide research is challenged by technical difficulties in identifying new bioactive peptides. Here the authors present an analytical pipeline for large-scale peptidomics applied to the rat hypothalamus, identifying thousands of endogenous neuropeptides and their post-translational modifications.

Anna Secher
Christian D. Kelstrup
Jesper V. Olsen
ResearchOpen Access04 May 2016
Nature Communications

Volume: 7, P: 1-10
The effect of fatty diacid acylation of human PYY_3-36 on Y₂ receptor potency and half-life in minipigs

Søren Østergaard
Johan F. Paulsson
Birgitte S. Wulff
ResearchOpen Access27 Oct 2021
Scientific Reports

Volume: 11, P: 1-15

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Hypothalamic CART is a new anorectic peptide regulated by leptin

CD8+ T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens

Analytic framework for peptidomics applied to large-scale neuropeptide identification

The effect of fatty diacid acylation of human PYY3-36 on Y2 receptor potency and half-life in minipigs

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CD8⁺ T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens

The effect of fatty diacid acylation of human PYY_3-36 on Y₂ receptor potency and half-life in minipigs