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Showing 1–4 of 4 results
Advanced filters: Author: Bjorn Askevold Clear advanced filters
  • One of the hurdles facing the development of effective catalysts to produce ammonia from nitrogen is the stability of the metal nitrides that form during the reaction. Now, the hydrogenolysis of nitride ligands with hydrogen is reported and attributed to PNP pincer ligand cooperativity.

    • Bjorn Askevold
    • Jorge Torres Nieto
    • Sven Schneider
    Research
    Nature Chemistry
    Volume: 3, P: 532-537
  • Palladium (Pd) is a well-known catalyst in organic chemistry but its use in nanomedicine is limited. Here, the authors design a Pd nanoparticle that triggers the activation of an antitumour prodrugin vivo, which shows efficacy and improves toxicity compared to traditional solvent- and nanoparticle-drug formulations.

    • Miles A. Miller
    • Bjorn Askevold
    • Ralph Weissleder
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-13
  • Coupling reactions of nitrogen atoms represent elementary steps to many important, heterogeneously catalysed reactions, such as the Haber–Bosch process or selective catalytic reduction of NOx to N2. Here, the synthesis and characterization of closed- and open-shell, square-planar iridium nitrido complexes is described, indicating considerable nitridyl radical character for the open shell complex.

    • Markus G. Scheibel
    • Bjorn Askevold
    • Sven Schneider
    Research
    Nature Chemistry
    Volume: 4, P: 552-558
  • Drug-loaded nanoparticles allow controlled release and enhanced delivery, yet understanding in vivobehavior has been difficult. Here, the authors develop a platinum prodrug coupled to a polymer platform, and use intravital imaging to show that the nanoparticle accumulates in macrophages, from the which drug redistributes to neighboring tumour cells.

    • Miles A. Miller
    • Yao-Rong Zheng
    • Ralph Weissleder
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13