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Showing 1–4 of 4 results
Advanced filters: Author: Blessy Paul Clear advanced filters
  • Phox homology (PX) domains are membrane interacting domains that bind to various lipids. Here authors screen all human PX domains systematically for their phospholipid preferences and define four classes and provide the basis for defining and predicting functional PX-membrane interactions.

    • Mintu Chandra
    • Yanni K.-Y. Chin
    • Brett M. Collins
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14
  • Lipolysis generates fatty acids that are burned in peroxisomes for energy, and dysregulation in this process creates toxic reactive oxygen species (ROS) and contributes to diseases such as non-alcoholic fatty liver disease. In this issue of Nature Metabolism, Ding et al. reveal how the peroxin PEX2 senses cellular ROS to fine-tune ATGL-mediated lipolysis.

    • Blessy Paul
    • W. Mike Henne
    News & Views
    Nature Metabolism
    Volume: 3, P: 1591-1593