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Showing 1–5 of 5 results

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Identification of novel USH2A mutations: implications for the structure of USH2A protein

Bo Dreyer
Lisbeth Tranebjærg
Øivind Nilssen
Research24 Jul 2000
European Journal of Human Genetics

Volume: 8, P: 500-506
Experimental determination of giant polarization in wurtzite III-nitride semiconductors

The authors provide experimental evidence for giant polarization in wurtzite III-nitrides, establishing a unified framework for understanding and engineering polarization in these materials and their functional device architectures.

Haotian Ye
Ping Wang
Xinqiang Wang
ResearchOpen Access24 Apr 2025
Nature Communications

Volume: 16, P: 1-10
A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAF^V600E colorectal tumors

Coppé and colleagues define a resistance mechanism to combination BRAF- and EGFR-targeted therapy in BRAF^V600E colorectal cancers that could be overcome in vitro and in vivo by repurposing COX2 inhibitors.

Ana Ruiz-Saenz
Chloe E. Atreya
Jean-Philippe Coppé
ResearchOpen Access09 Feb 2023
Nature Cancer

Volume: 4, P: 240-256
Use of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein

Chien-Chiao Huang
Kai-Wen Cheng
Tian-Lu Cheng
ResearchOpen Access09 Jul 2019
Scientific Reports

Volume: 9, P: 1-11
Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities

Coppé and colleagues design a peptide phosphorylation-screening system that simultaneously measures the enzymatic activity of multiple kinases, identifying mechanisms of therapy resistance and druggable targets in colorectal cancer and melanoma.

Jean-Philippe Coppé
Miki Mori
Laura J. van ‘t Veer
Research03 Jun 2019
Nature Cell Biology

Volume: 21, P: 778-790