The characteristics of the cell type(s) responsible for initiating protective gut immune responses are not fully defined. Akira and colleagues show that TLR5+ lamina propria dendritic cells trigger, in a retinoic-dependent way, the production of interleukin 17 and immunoglobulin A.
- Satoshi Uematsu
- Kosuke Fujimoto
- Shizuo Akira
