Nature Search

Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans

John Collins
Bonnie Saari
Philip Anderson
Research20 Aug 1987
Nature

Volume: 328, P: 726-728
Electron flow in hydrogenotrophic methanogens under nickel limitation

Two distantly related methanogens shift the methanogenic pathway under nickel limitation, suggesting that methanogens adapt to changing bioavailability of nickel by rerouting electron flow between two different pathways.

Shunsuke Nomura
Pablo San Segundo-Acosta
Seigo Shima
ResearchOpen Access02 Jul 2025
Nature

Volume: 644, P: 490-496
Publisher Correction: Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli

Ralf Steinhilper
Gabriele Höff
Bonnie J. Murphy
Amendments and CorrectionsOpen Access25 Nov 2022
Nature Communications

Volume: 13, P: 1
Two-stage binding of mitochondrial ferredoxin-2 to the core iron-sulfur cluster assembly complex

De novo [2Fe-2S] cluster synthesis by the mitochondrial ISC complex requires electrons from ferredoxin-2 (FDX2). The authors map FDX2 binding to the core ISC complex, showing that FDX2 can bind in two possible conformations in a manner competitive with frataxin.

Ralf Steinhilper
Linda Boß
Bonnie J. Murphy
ResearchOpen Access04 Dec 2024
Nature Communications

Volume: 15, P: 1-14
Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase

Using cryo-electron microscopy, the authors obtained structures of Streptococcus pneumoniae nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in different states. Combined with site-directed mutagenesis and biochemical assays, the structures shed light on the activity and regulation of NADPH oxidases.

Victor R. A. Dubach
Pablo San Segundo-Acosta
Bonnie J. Murphy
ResearchOpen Access22 Jul 2024
Nature Structural & Molecular Biology

Volume: 31, P: 1769-1777
Elemental mapping in single-particle reconstructions by reconstructed electron energy-loss analysis

An approach combining electron energy-loss spectroscopy with image processing tools from single-particle cryo-electron microscopy enables elemental mapping in macromolecular complexes, paving the way for the accurate assignment of metals, ions, ligands and lipids.

Olivia Pfeil-Gardiner
Higor Vinícius Dias Rosa
Bonnie J. Murphy
ResearchOpen Access24 Oct 2024
Nature Methods

Volume: 21, P: 2299-2306
Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2

The biogenesis of iron-sulfur proteins in eukaryotes is initiated by the mitochondrial core ISC complex. Here, the authors provide structural, biochemical and spectroscopic data to characterize sulfur transfer intermediates in the core ISC complex.

Vinzent Schulz
Ralf Steinhilper
Roland Lill
ResearchOpen Access16 Apr 2024
Nature Communications

Volume: 15, P: 1-15
Cromolyn Sodium Decreases the Pulmonary Vascular Response to Alveolar Hypoxia in Lambs

Bonnie J Taylor
James E Fewell
Donald E Hill
Research01 Sept 1986
Pediatric Research

Volume: 20, P: 834-837
Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli

New cryo-EM structures of the formate hydrogenlyase complex from the model bacterium E. coli clarify how electrons and protons move through the complex and are combined to make H2 gas. The complex shows important similarities and differences to related bioenergetic complexes across the tree of life.

Ralf Steinhilper
Gabriele Höff
Bonnie J. Murphy
ResearchOpen Access14 Sept 2022
Nature Communications

Volume: 13, P: 1-13
Successful kinetic impact into an asteroid for planetary defence

The impact of the DART spacecraft on the asteroid Dimorphos is reported and reconstructed, demonstrating that kinetic impactor technology is a viable technique to potentially defend Earth from asteroids.

R. Terik Daly
Carolyn M. Ernst
Yun Zhang
ResearchOpen Access01 Mar 2023
Nature

Volume: 616, P: 443-447
Previous parity differentially influences cognition in later life depending on dementia status

Bonnie H. Lee
Cindy K. Barha
Liisa A. M. Galea
ResearchOpen Access10 Oct 2025
npj Dementia

Volume: 1, P: 1-13
The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

The BIN1 SNP rs744373 is associated with higher CSF tau and phosphorylated tau levels. Here the authors show, using PET imaging, that this SNP is associated with tau accumulation in the brain as well as impaired memory in older individuals without dementia.

Nicolai Franzmeier
Anna Rubinski
Ansgar J. Furst
ResearchOpen Access16 Apr 2019
Nature Communications

Volume: 10, P: 1-12
Depressive Response to Physostigmine Challenge in Borderline Personality Disorder Patients

Bonnie J Steinberg
Robert Trestman
Larry J Siever
Research01 Oct 1997
Neuropsychopharmacology

Volume: 17, P: 264-273
Unsupervised data-driven stratification of mentalizing heterogeneity in autism

Michael V. Lombardo
Meng-Chuan Lai
Simon Baron-Cohen
ResearchOpen Access18 Oct 2016
Scientific Reports

Volume: 6, P: 1-15
Imbalanced social-communicative and restricted repetitive behavior subtypes of autism spectrum disorder exhibit different neural circuitry

Natasha Bertelsen et al. develop a computational model to categorize patients with autism spectrum disorder (ASD) into distinct subgroups, based on social-communicative or restricted repetitive behaviors. By integrating publicly available neuroimaging and genetic data, they report neural and molecular signatures in two of these subgroups, altogether highlighting subtle differences in neural circuitry and genomic networks that could underlie phenotypic differences among ASD patients.

Natasha Bertelsen
Isotta Landi
Michael V. Lombardo
ResearchOpen Access14 May 2021
Communications Biology

Volume: 4, P: 1-13
Quantifying neurologic disease using biosensor measurements in-clinic and in free-living settings in multiple sclerosis

Tanuja Chitnis
Bonnie I. Glanz
Thomas M. Snyder
ResearchOpen Access11 Dec 2019
npj Digital Medicine

Volume: 2, P: 1-8
HormoneBase, a population-level database of steroid hormone levels across vertebrates

Maren N. Vitousek
Michele A. Johnson
Tony D. Williams
ResearchOpen Access22 May 2018
Scientific Data

Volume: 5, P: 1-7
RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

Adam Penn-Nicholson
Stanley Kimbung Mbandi
Lara Lewis
ResearchOpen Access25 May 2020
Scientific Reports

Volume: 10, P: 1-21

Search

Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans

Electron flow in hydrogenotrophic methanogens under nickel limitation

Publisher Correction: Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli

Two-stage binding of mitochondrial ferredoxin-2 to the core iron-sulfur cluster assembly complex

Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase

Elemental mapping in single-particle reconstructions by reconstructed electron energy-loss analysis

Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2

Cromolyn Sodium Decreases the Pulmonary Vascular Response to Alveolar Hypoxia in Lambs

Structure of the membrane-bound formate hydrogenlyase complex from Escherichia coli

Successful kinetic impact into an asteroid for planetary defence

Previous parity differentially influences cognition in later life depending on dementia status

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

Depressive Response to Physostigmine Challenge in Borderline Personality Disorder Patients

Unsupervised data-driven stratification of mentalizing heterogeneity in autism

Imbalanced social-communicative and restricted repetitive behavior subtypes of autism spectrum disorder exhibit different neural circuitry

Quantifying neurologic disease using biosensor measurements in-clinic and in free-living settings in multiple sclerosis

HormoneBase, a population-level database of steroid hormone levels across vertebrates

RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

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