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Showing 1–10 of 10 results

Advanced filters: Author: Bonsu Ku Clear advanced filters

Bacterial collagenase harnesses collagen geometry for processive cleavage

Collagen forms a tough triple helix that resists enzymes. Structural analysis suggests a bacterial collagenase grips the helix, loosens one strand for cutting, and uses intact strands as tracks to ratchet forward step by step.

Hiroya Oki
Katsuki Takebe
Kazuki Kawahara
ResearchOpen Access02 Apr 2026
Nature Communications

P: 1-13
Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis

Plk4 regulates centriole duplication. Two centrosomal scaffold proteins, Cep192 and Cep152, are shown to interact with Plk4 in a temporally and spatially regulated manner, and structural analyses reveal that these interactions are mutually exclusive.

Suk-Youl Park
Jung-Eun Park
Kyung S Lee
Research29 Jun 2014
Nature Structural & Molecular Biology

Volume: 21, P: 696-703
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

Chengyu Liang
Pinghui Feng
Jae U. Jung
Research25 Jun 2006
Nature Cell Biology

Volume: 8, P: 688-698
Nurr1 performs its anti-inflammatory function by regulating RasGRP1 expression in neuro-inflammation

Mihee Oh
Sun Young Kim
Baek-Soo Han
ResearchOpen Access01 Jul 2020
Scientific Reports

Volume: 10, P: 1-17
Insights into the recognition mechanism in the UBR box of UBR4 for its specific substrates

The UBR4 UBR box can bind not only to type 1 N-degron, such as arginine, but also to amino acids with aromatic rings belonging to type 2 N-degrons, and this interaction occurs through pi-interactions.

Da Eun Jeong
Hye Seon Lee
Ho-Chul Shin
ResearchOpen Access29 Nov 2023
Communications Biology

Volume: 6, P: 1-14
Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells

Structural-, biophysical- and imaging data show that self-assembly of the pericentrosomal proteins Cep63 and Cep152 is a stepwise and concentration-dependent process and that a defect in this event disrupts proper Plk4-mediated centriole duplication

Jong Il Ahn
Liang Zhang
Kyung S. Lee
ResearchOpen Access11 Jul 2023
Communications Biology

Volume: 6, P: 1-20
Influenza viral matrix 1 protein aggravates viral pathogenicity by inducing TLR4-mediated reactive oxygen species production and apoptotic cell death

Chang-Ung Kim
Dahwan Lim
Doo-Jin Kim
ResearchOpen Access30 Mar 2023
Cell Death & Disease

Volume: 14, P: 1-12
Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera

Kidae Kim
Dong Ho Lee
Jeong-Hoon Kim
ResearchOpen Access23 Dec 2019
Scientific Reports

Volume: 9, P: 1-14
Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX

Bonsu Ku
Chengyu Liang
Byung-Ha Oh
Research09 Nov 2010
Cell Research

Volume: 21, P: 627-641
Author Correction: Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells

Jong Il Ahn
Liang Zhang
Kyung S. Lee
Amendments and CorrectionsOpen Access27 Jul 2023
Communications Biology

Volume: 6, P: 1-4