The authors established a bioinformatics approach to assessing the impact of melanoma mutants, among a set of extra-cellular matrix structural proteins, on the sensitivity of matrix metalloproteinase-2 (MMP2), extensively associated with melanoma. Results indicate that tumor samples with mutant amino acids adjacent to MMP2 sites also represented a better survival rate.
- Saif Zaman
- Boris I. Chobrutskiy
- George Blanck
