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Showing 1–6 of 6 results

Advanced filters: Author: Brad Doble Clear advanced filters

A group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing

Werbowetski-Ogilvie, Taylor and colleagues report a noncanonical role for OTX2 in regulating alternative splicing and controlling a stem cell and pro-tumorigenic splicing program in group 3 medulloblastoma.

Olivier Saulnier
Jamie Zagozewski
Tamra E. Werbowetski-Ogilvie
ResearchOpen Access18 Jul 2024
Nature Cell Biology

Volume: 26, P: 1233-1246
Failure of human rhombic lip differentiation underlies medulloblastoma formation

Derailed differentiation of human-specific progenitors of the developing cerebellar rhombic lip is the cause of group 4 medulloblastoma, the most common childhood brain tumour.

Liam D. Hendrikse
Parthiv Haldipur
Michael D. Taylor
Research21 Sept 2022
Nature

Volume: 609, P: 1021-1028
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

Xin Zeng
Keiko Tamai
Xi He
Research08 Dec 2005
Nature

Volume: 438, P: 873-877
Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation

Liam D. Hendrikse
Parthiv Haldipur
Michael D. Taylor
Amendments and Corrections29 Nov 2022
Nature

Volume: 612, P: E12
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda
Leon Chalil
Karun K. Singh
ResearchOpen Access06 Jan 2023
Molecular Psychiatry

Volume: 28, P: 1747-1769
BMI1 is a therapeutic target in recurrent medulloblastoma

David Bakhshinyan
Chitra Venugopal
Sheila K. Singh
Research22 Oct 2018
Oncogene

Volume: 38, P: 1702-1716