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Showing 1–7 of 7 results
Advanced filters: Author: Brad E. Pfeiffer Clear advanced filters

  • It is known that compressed sequences of hippocampal place cells can ‘replay’ previous navigational trajectories in linearly constrained mazes; here, rat place-cell sequences representing two-dimensional spatial trajectories were observed before navigational decisions, and predicted the immediate navigational path.

    • Brad E. Pfeiffer
    • David J. Foster
    Research
    Nature
    Volume: 497, P: 74-79

  • The authors find that the Avpr1a gene, encoding the vasopressin-1A receptor, is responsible for strain-dependent pain sensitivity of mice to formalin and capsaicin. In humans, a single nucleotide polymorphism in AVPR1A was found to affect capsaicin pain and desmopressin analgesia. In both species, the effects were male specific and dependent on stress levels at the time of testing.

    • Jeffrey S Mogil
    • Robert E Sorge
    • Roger B Fillingim
    Research
    Nature Neuroscience
    Volume: 14, P: 1569-1573

  • Neuronal assemblies remain understudied in human data. Here, the authors show that gamma phase-locked neuronal firing sequences comprise assemblies in human single unit recordings, and their ability to incorporate new neurons over time facilitates memory.

    • Gray Umbach
    • Ryan Tan
    • Bradley Lega
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-11

  • Kelly et al. describe two cerebellum–thalamus–mPFC pathways in mice that regulate social and repetitive behavior. PC activation in Rcrus1 and posterior vermis improved social and reduced repetitive behaviors, respectively, in PC-Tsc1 mutant mice.

    • Elyza Kelly
    • Fantao Meng
    • Peter T. Tsai
    Research
    Nature Neuroscience
    Volume: 23, P: 1102-1110

  • The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

    • Tim H. H. Coorens
    • Ji Won Oh
    • Yuqing Wang
    Reviews
    Nature
    Volume: 643, P: 47-59

  • The developmental Genotype-Tissue Expression (dGTEx) projects will catalogue and integrate gene expression, regulation and genetics data across 120 human donors from birth to adulthood with developmentally matched non-human primates, including 126 rhesus macaques and 72 common marmosets.

    • Tim H. H. Coorens
    • Amy Guillaumet-Adkins
    • Sige Zou
    Reviews
    Nature
    Volume: 637, P: 557-564