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Showing 1–6 of 6 results
Advanced filters: Author: Bram Vrancken Clear advanced filters

  • This study on respiratory syncytial virus (RSV) reveals global genomic gaps. Using INFORM-RSV data, it uncovers selection’s impact on RSVA and RSVB diversity. Analysing full genomes, it highlights non-neutral epidemic processes. The research emphasises air travel’s influence on global spread, underscoring the need for comprehensive RSV genomic surveillance.

    • Annefleur C. Langedijk
    • Bram Vrancken
    • Shabir A. Madhi
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12

  • For archival pathogens, like pH1N1 Influenza A virus the causative agent of 1918/19 pandemic, only few whole genome sequences exist. Here, Patrono et al. provide one complete and two partial genomes from Germany and find variation in two sites in the nucleoprotein gene in pandemic samples compared to pre-pandemic samples, that are associated with resistance to host antiviral response, pointing at a possible viral adaptation to humans.

    • Livia V. Patrono
    • Bram Vrancken
    • Sébastien Calvignac-Spencer
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-9

  • Classical epidemiological approaches have been limited in their ability to formally test hypotheses. Here, Dellicour et al. illustrate how phylodynamic and phylogeographic analyses can be leveraged for hypothesis testing in molecular epidemiology using West Nile virus in North America as an example.

    • Simon Dellicour
    • Sebastian Lequime
    • Philippe Lemey
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • The role of Africa in the global spread of highly pathogenic avian influenza (HPAI) is not well understood. Here, using evolutionary analyses, the authors show that Africa mainly acts as ecological sink for HPAI H5, and reveal varying paths of HPAI incursions either through domestic or wild birds.

    • Alice Fusaro
    • Bianca Zecchin
    • Isabella Monne
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13

  • It is currently unknown how climate and land use changes could affect the endemic area of Lassa virus, a zoonotic pathogen responsible for Lassa fever. Here, the authors show that by 2070, new regions in Africa will likely become ecologically suitable for Lassa virus, drastically increasing the population living in conditions favourable for virus circulation.

    • Raphaëlle Klitting
    • Liana E. Kafetzopoulou
    • Simon Dellicour
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15