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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer

Liquid biopsies could be valuable tools to monitor breast cancer progression and evolution. Here, the authors investigate genomic profiling of tissue and liquid biopsies in a large cohort of patients with breast cancer during the course of therapy to characterise tumour evolution and acquired mutations.

Smruthy Sivakumar
Dexter X. Jin
Ethan S. Sokol
ResearchOpen Access05 Dec 2022
Nature Communications

Volume: 13, P: 1-13
Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens

Cancer vaccines that self-assemble into uniform nanoparticles improve tumor clearance.

Geoffrey M. Lynn
Christine Sedlik
Robert A. Seder
Research13 Jan 2020
Nature Biotechnology

Volume: 38, P: 320-332
Activating IGF1R hotspot non-frameshift insertions define a novel, potentially targetable molecular subtype of adenoid cystic carcinoma

Matthew Margolis
Tyler Janovitz
Brennan Decker
Research15 Aug 2022
Modern Pathology

Volume: 35, P: 1618-1623
Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology

Being man’s best friend, dogs have been bred and selected for certain morphologic traits and breed-associated behaviours. Here, Plassais et al. analyse 722 canine whole genome sequences including modern breeds, wild canids and village dogs by GWAS and search for signatures of selection.

Jocelyn Plassais
Jaemin Kim
Elaine A. Ostrander
ResearchOpen Access02 Apr 2019
Nature Communications

Volume: 10, P: 1-14
Pan-tumor validation of a NGS fraction-based MSI analysis as a predictor of response to Pembrolizumab

Douglas I. Lin
Julia C. F. Quintanilha
Amy K. Wehn
ResearchOpen Access14 Sept 2024
npj Precision Oncology

Volume: 8, P: 1-9
Clinicopathological and genomic characterization of BCORL1-driven high-grade endometrial stromal sarcomas

Douglas I. Lin
Richard S. P. Huang
Julia A. Elvin
Research23 Jul 2021
Modern Pathology

Volume: 34, P: 2200-2210
Making a definitive diagnosis: Successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease

Elizabeth A Worthey
Alan N Mayer
David P Dimmock
Research17 Dec 2010
Genetics in Medicine

Volume: 13, P: 255-262

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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer

Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens

Activating IGF1R hotspot non-frameshift insertions define a novel, potentially targetable molecular subtype of adenoid cystic carcinoma

Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology

Pan-tumor validation of a NGS fraction-based MSI analysis as a predictor of response to Pembrolizumab

Clinicopathological and genomic characterization of BCORL1-driven high-grade endometrial stromal sarcomas

Making a definitive diagnosis: Successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease

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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer

Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens

Activating IGF1R hotspot non-frameshift insertions define a novel, potentially targetable molecular subtype of adenoid cystic carcinoma

Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology

Pan-tumor validation of a NGS fraction-based MSI analysis as a predictor of response to Pembrolizumab

Clinicopathological and genomic characterization of BCORL1-driven high-grade endometrial stromal sarcomas

Making a definitive diagnosis: Successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease

Search

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