Nature Search

Learning neuroimaging models from health system-scale data

Prima is an AI foundation model for neuroimaging based on clinical magnetic resonance imaging that offers accurate and explainable diagnostics, worklist priority for radiologists and clinical referral recommendations with equitable performance on diverse groups.

Yiwei Lyu
Samir Harake
Todd Hollon
Research06 Feb 2026
Nature Biomedical Engineering

P: 1-13
VO: Vaccine Ontology

Yongqun He
Lindsay Cowell
Barry Smith
ResearchOpen Access05 Aug 2009
Nature Precedings

P: 1
SEA CDM: Study-Experiment-Assay Common Data Model and Databases for Cross-Domain Data Integration and Analysis

Anthony Huffman
Feng-Yu Yeh
Yongqun He
ResearchOpen Access14 Jan 2026
Scientific Data

Volume: 13, P: 1-14
VO: Vaccine Ontology

Yongqun He
Lindsay Cowell
Barry Smith
MultimediaOpen Access05 Aug 2009
Nature Precedings

P: 1
Improving the representativeness of UK’s national COVID-19 Infection Survey through spatio-temporal regression and post-stratification

Estimates of infection rates from the UK COVID-19 Infection Survey may have been biased by the characteristics of people who chose to take part. Here, the authors show that the survey population had unusually high vaccination rates and adjust infection estimates taking this into account.

Koen B. Pouwels
David W. Eyre
Chris Cunningham
ResearchOpen Access24 Jun 2024
Nature Communications

Volume: 15, P: 1-12
Identification of undetected SARS-CoV-2 infections by clustering of Nucleocapsid antibody trajectories

Many SARS-CoV-2 infections may go undetected through conventional PCR or lateral flow tests. Here, the authors analyse the utility of analysing longitudinal nucleocapsid antibody trajectories to improve identification of prior SARS-CoV-2 infections using surveillance data from the UK.

Leslie R. Zwerwer
Tim E. A. Peto
Chris Cunningham
ResearchOpen Access14 May 2025
Nature Communications

Volume: 16, P: 1-13
Risk of SARS-CoV-2 reinfection during multiple Omicron variant waves in the UK general population

The factors influencing risk of reinfection with SARS-CoV-2 are poorly understood. Here, the authors use data from the UK COVID-19 Infection Survey, a community based longitudinal study, to assess characteristics of ~45,000 reinfections compared to initial infections.

Jia Wei
Nicole Stoesser
Chris Cunningham
ResearchOpen Access02 Feb 2024
Nature Communications

Volume: 15, P: 1-14
SARS-CoV-2 antibody trajectories after a single COVID-19 vaccination with and without prior infection

The impact of prior infection on the immune response to COVID-19 vaccination has not been fully characterised. Here, the authors use data from ~100,000 adults in the UK and find that a single vaccine dose in those with prior infection produces a comparable or stronger response to two doses in those without infection.

Jia Wei
Philippa C. Matthews
Chris Cunningham
ResearchOpen Access29 Jun 2022
Nature Communications

Volume: 13, P: 1-9
Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom

Longitudinal tracing of antibody responses to the ChAdOx1 and the BNT162b2 COVID-19 vaccines in 45,965 adults from the United Kingdom give indications for vaccine prioritization.

Jia Wei
Nicole Stoesser
Jessica Lee
ResearchOpen Access21 Jul 2021
Nature Microbiology

Volume: 6, P: 1140-1149
Anti-spike antibody response to natural SARS-CoV-2 infection in the general population

Most people who are infected with SARS-CoV-2 seroconvert within a few weeks, but the determinants and duration of the antibody response are not known. Here, the authors characterise these features of the immune response using data from a large representative community sample of the UK population.

Jia Wei
Philippa C. Matthews
Chris Cunningham
ResearchOpen Access29 Oct 2021
Nature Communications

Volume: 12, P: 1-12
Protection against SARS-CoV-2 Omicron BA.4/5 variant following booster vaccination or breakthrough infection in the UK

The duration and strength of protection against SARS-CoV-2 infection resulting from a booster vaccine dose or breakthrough infection are not well understood. This study uses data from the UK COVID-19 Infection Survey to investigate correlates of protection against Omicron BA.4/5 infection and assess antibody responses to booster vaccination and breakthrough infections.

Jia Wei
Philippa C. Matthews
Chris Cunningham
ResearchOpen Access16 May 2023
Nature Communications

Volume: 14, P: 1-15
Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines

A large study in the United Kingdom shows that virus-specific antibody levels associated with at least 67% protection against SARS-CoV-2 Delta variant infection last longer after two doses of BNT162b2 vaccine than after two doses of ChAdOx1 vaccine in previously uninfected individuals.

Jia Wei
Koen B. Pouwels
Chris Cunningham
ResearchOpen Access14 Feb 2022
Nature Medicine

Volume: 28, P: 1072-1082
Contrasting maternal and paternal genetic histories among five ethnic groups from Khyber Pakhtunkhwa, Pakistan

Muhammad Tariq
Habib Ahmad
Theodore G. Schurr
ResearchOpen Access19 Jan 2022
Scientific Reports

Volume: 12, P: 1-18
Publisher Correction: 3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification

Alexandr A. Kalinin
Ari Allyn-Feuer
Ivo D. Dinov
Amendments and CorrectionsOpen Access26 Oct 2018
Scientific Reports

Volume: 8, P: 1
Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies

Aikaterini Alexaki
Gaya K. Hettiarachchi
Chava Kimchi-Sarfaty
ResearchOpen Access29 Oct 2019
Scientific Reports

Volume: 9, P: 1-15
3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification

Alexandr A. Kalinin
Ari Allyn-Feuer
Ivo D. Dinov
ResearchOpen Access12 Sept 2018
Scientific Reports

Volume: 8, P: 1-14
CIDO, a community-based ontology for coronavirus disease knowledge and data integration, sharing, and analysis

The Coronavirus Infectious Disease Ontology (CIDO) is a community-based ontology that supports coronavirus disease knowledge and data standardization, integration, sharing, and analysis.

Yongqun He
Hong Yu
Barry Smith
Comments & OpinionOpen Access12 Jun 2020
Scientific Data

Volume: 7, P: 1-5
An Examination of Rostral Anterior Cingulate Cortex Function and Neurochemistry in Obsessive–Compulsive Disorder

Brian P Brennan
Olga Tkachenko
Scott L Rauch
Research09 Feb 2015
Neuropsychopharmacology

Volume: 40, P: 1866-1876

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